{"id":671815,"date":"2026-01-16T19:46:04","date_gmt":"2026-01-16T19:46:04","guid":{"rendered":"https:\/\/microscopemedia.com\/?p=671815"},"modified":"2026-01-16T19:46:04","modified_gmt":"2026-01-16T19:46:04","slug":"tratamentul-cancerului-infantil-inspirat-de-o-jucarie-populara-se-potrivesc-ca-o-cheie-intr-o-incuietoare","status":"publish","type":"post","link":"https:\/\/microscopemedia.com\/?p=671815","title":{"rendered":"Tratamentul cancerului infantil, inspirat de o juc\u0103rie popular\u0103. \u201eSe potrivesc ca o cheie \u00eentr-o \u00eencuietoare\u201d"},"content":{"rendered":"
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O echip\u0103 de cercet\u0103tori a dezvoltat o nou\u0103 strategie de tratament al neuroblastomului care combin\u0103 nanotehnologia cu terapia celular\u0103. Folosind lipozomi modifica\u021bi cu \u201emolecule clic\u201d sau \u201ede tip LEGO\u201d, noua metod\u0103 este capabil\u0103 s\u0103 g\u0103seasc\u0103 \u0219i s\u0103 elimine celulele canceroase \u00een mod eficient, noteaz\u0103 El Economista<\/a>.<\/p>\n

Neuroblastomul este cancerul infantil cu cel mai prost prognostic. \u00cen prezent, nu se cunoa\u0219te o terapie complet eficient\u0103, iar principala problem\u0103 este lipsa de selectivitate. Terapiile celulare administreaz\u0103 celule vii capabile s\u0103 dezvolte noi func\u021bii. Dar, aceste celule nu sunt adesea capabile s\u0103 disting\u0103 celulele bolnave de cele s\u0103n\u0103toase.<\/p>\n

Molecule care se recunosc f\u0103r\u0103 echivoc<\/h2>\n

Studiul a fost realizat de cercet\u0103tori de la Universitatea Politehnic\u0103 din Madrid, de la Spitalul Universitar de Copii Ni\u00f1o Jes\u00fas \u0219i de la Institutului de S\u0103n\u0103tate Carlos III. Echipa de nanotehnologie organic\u0103 a modificat suprafa\u021ba celulelor de neuroblastom \u0219i a unui tip de celule imunitare ale pacientului.<\/p>\n

Grupurile introduse pe suprafa\u021ba celulelor<\/a> apar\u021bin unui tip de molecule cunoscute sub numele de \u201emolecule clic\u201d sau \u201etip LEGO\u201d. Acestea se potrivesc \u00eentre ele ca o cheie \u00eentr-o \u00eencuietoare \u0219i se unesc numai cu grupul complementar. C\u00e2nd celulele imune cu acest tip de molecul\u0103 ajung la tumor\u0103, vor fi capabile s\u0103 g\u0103seasc\u0103 f\u0103r\u0103 echivoc celulele tumorale, marcate cu \u201eclic\u201d complementar.<\/p>\n

Modific\u0103rile superficiale se realizeaz\u0103 folosind nanoparticule lipozomale. Acestea pot transporta \u00een interiorul lor medicamente capabile s\u0103 sl\u0103beasc\u0103 sau chiar s\u0103 ucid\u0103 celulele tumorale \u0219i s\u0103 activeze macrofagele.<\/p>\n

Terapie adaptabil\u0103 pentru alte tipuri de cancer<\/h2>\n

Sandra Jim\u00e9nez, cercet\u0103toare la Universitatea Politehnic\u0103 din Madrid, a subliniat c\u0103 cercetarea deschide calea c\u0103tre terapii mult mai eficiente \u0219i selective. Noua platform\u0103 este adaptabil\u0103 \u0219i promite s\u0103 func\u021bioneze nu numai pentru neuroblastom, ci \u0219i pentru alte tipuri de tumori.<\/p>\n

At\u00e2t elementele de recunoa\u0219tere a celulelor \u021bint\u0103, c\u00e2t \u0219i medicamentele pot fi adaptate \u00een func\u021bie de tipul de tumor\u0103 care trebuie tratat\u0103. Aceast\u0103 flexibilitate face din noua strategie o op\u021biune promi\u021b\u0103toare \u00een lupta \u00eempotriva cancerului infantil.<\/p>\n","protected":false},"excerpt":{"rendered":"

O echip\u0103 de cercet\u0103tori a dezvoltat o nou\u0103 strategie de tratament al neuroblastomului care combin\u0103 nanotehnologia cu terapia celular\u0103. Folosind lipozomi modifica\u021bi cu \u201emolecule clic\u201d sau \u201ede tip LEGO\u201d, noua … Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":671816,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts\/671815"}],"collection":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=671815"}],"version-history":[{"count":0,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts\/671815\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/media\/671816"}],"wp:attachment":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=671815"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=671815"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=671815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}