{"id":689114,"date":"2026-04-24T20:16:04","date_gmt":"2026-04-24T20:16:04","guid":{"rendered":"https:\/\/microscopemedia.com\/?p=689114"},"modified":"2026-04-24T20:16:04","modified_gmt":"2026-04-24T20:16:04","slug":"medicamentul-pentru-colesterol-care-a-socat-oamenii-de-stiinta-ar-putea-influenta-procesul-de-imbatranire","status":"publish","type":"post","link":"https:\/\/microscopemedia.com\/?p=689114","title":{"rendered":"Medicamentul pentru colesterol care a \u0219ocat oamenii de \u0219tiin\u021b\u0103: ar putea influen\u021ba procesul de \u00eemb\u0103tr\u00e2nire"},"content":{"rendered":"
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Cercetarea, publicat\u0103 \u00een revista Pharmacological Research<\/a>, arat\u0103 c\u0103 medicamentul \u00eembun\u0103t\u0103\u021be\u0219te aspecte cognitive, precum memoria \u0219i \u00eenv\u0103\u021barea, dar \u0219i capacitatea inimii de a pompa s\u00e2ngele odat\u0103 cu \u00eenaintarea \u00een v\u00e2rst\u0103<\/strong>, potrivit unui comunicat transmis mar\u021bi de UIC Barcelona.<\/p>\n

Cercet\u0103toarea din cadrul Departamentului de \u0218tiin\u021be Biomedicale al UIC Barcelona, N\u00faria Casals, care a participat la studiu, a explicat c\u0103, la nivel molecular, medicamentul prelunge\u0219te telomerii \u0219i reduce senescen\u021ba celular\u0103, ceea ce \u201ear putea \u00eensemna o reducere a \u00eemb\u0103tr\u00e2nirii \u021besuturilor\u201d.<\/p>\n

\u201eEfecte benefice\u201d \u0219i asupra osteoartritei<\/h2>\n

\u201eTratamentul cu acest medicament reduce acumularea de lipide peroxidate asociate v\u00e2rstei \u0219i \u00eembun\u0103t\u0103\u021be\u0219te func\u021bia mitocondriilor, structurile celulare responsabile de producerea energiei\u201d, a rezumat Casals, care este \u0219i profesoar\u0103 de farmacologie \u0219i lider al Grupului de Cercetare \u201eFrom Cell Metabolism to Metabolic Diseases\u201d (Metadis) din cadrul UIC Barcelona.<\/p>\n

Pe l\u00e2ng\u0103 faptul c\u0103 duce fiziologic la o \u00eembun\u0103t\u0103\u021bire a func\u021biei cardiace<\/a> \u0219i a func\u021biei cognitive cerebrale, cercet\u0103toarea a precizat c\u0103 al\u021bi autori au atribuit fenofibratului \u201eefecte benefice\u201d \u0219i asupra osteoartritei.<\/p>\n

Deocamdat\u0103, toate testele au fost realizate pe aceste animale<\/h2>\n

Autorii explic\u0103 faptul c\u0103 efectele depind de activarea a dou\u0103 proteine regulatoare ale metabolismului lipidic, PPAR-alfa \u0219i CPT1C.<\/p>\n

Casals, \u00eempreun\u0103 cu coordonatoarea studiului, Huichang Bi, de la Southern Medical University, a studiat timp de peste 10 ani proteina CPT1C, iar acum demonstreaz\u0103 \u201erolul esen\u021bial\u201d al acesteia ca mediator \u00een \u00eencetinirea \u00eemb\u0103tr\u00e2nirii la \u0219oarecii trata\u021bi cu fenofibrat.<\/p>\n

Deocamdat\u0103, toate testele au fost realizate pe aceste animale, \u00eens\u0103 autorii subliniaz\u0103 c\u0103 medicamentul \u201ear putea fi evaluat \u00een viitor ca o posibil\u0103 terapie pentru \u00eent\u00e2rzierea deterior\u0103rii asociate v\u00e2rstei\u201d, av\u00e2nd \u00een vedere c\u0103 este un medicament sigur \u0219i deja prescris oamenilor.<\/p>\n

\u201eDup\u0103 aceste rezultate ob\u021binute pe animale, vedem c\u0103 modularea metabolismului lipidic prin intermediul acestor proteine ar putea fi o strategie eficient\u0103 pentru a combate unele procese ale \u00eemb\u0103tr\u00e2nirii naturale\u201d, a explicat Casals, care subliniaz\u0103 c\u0103, pentru o \u00eemb\u0103tr\u00e2nire s\u0103n\u0103toas\u0103, este important\u0103 \u0219i activitatea fizic\u0103, precum \u0219i stimularea creierului.<\/p>\n","protected":false},"excerpt":{"rendered":"

Cercetarea, publicat\u0103 \u00een revista Pharmacological Research, arat\u0103 c\u0103 medicamentul \u00eembun\u0103t\u0103\u021be\u0219te aspecte cognitive, precum memoria \u0219i \u00eenv\u0103\u021barea, dar \u0219i capacitatea inimii de a pompa s\u00e2ngele odat\u0103 cu \u00eenaintarea \u00een v\u00e2rst\u0103, potrivit … Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":689115,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts\/689114"}],"collection":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=689114"}],"version-history":[{"count":0,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts\/689114\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/media\/689115"}],"wp:attachment":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=689114"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=689114"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=689114"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}