{"id":704409,"date":"2026-07-23T02:36:03","date_gmt":"2026-07-23T02:36:03","guid":{"rendered":"https:\/\/microscopemedia.com\/?p=704409"},"modified":"2026-07-23T02:36:03","modified_gmt":"2026-07-23T02:36:03","slug":"inima-are-un-mic-creier-propriu-care-o-protejeaza-in-situatii-de-stres","status":"publish","type":"post","link":"https:\/\/microscopemedia.com\/?p=704409","title":{"rendered":"Inima are un \u201emic creier\u201d propriu care o protejeaz\u0103 \u00een situa\u021bii de stres"},"content":{"rendered":"
\n
<\/div>\n<\/p><\/div>\n

Rezultatele studiului, publicate miercuri \u00een revista Cell, ar putea deschide calea c\u0103tre noi tratamente pentru bolile cardiovasculare.<\/p>\n

Sistemul nervos intrinsec al inimii este alc\u0103tuit dintr-o re\u021bea de neuroni localiza\u021bi \u00een \u021besutul adipos din jurul inimii. Ace\u0219tia comunic\u0103 at\u00e2t \u00eentre ei, c\u00e2t \u0219i cu creierul, fiind ultima verig\u0103 \u00een controlul func\u021biei cardiace.<\/p>\n

Folosind \u0219oareci modifica\u021bi genetic, cercet\u0103torii au identificat dou\u0103 subtipuri distincte de neuroni cardiaci.<\/p>\n

Primul grup, denumit Npy+, ac\u021bioneaz\u0103 ca o \u201efr\u00e2n\u0103\u201d pentru inim\u0103. Atunci c\u00e2nd ace\u0219ti neuroni au fost stimula\u021bi, ritmul cardiac al \u0219oarecilor a \u00eencetinit. \u00cen schimb, eliminarea lor a provocat insuficien\u021b\u0103 cardiac\u0103 \u0219i moartea animalelor, demonstr\u00e2nd c\u0103 sunt indispensabili pentru func\u021bionarea normal\u0103 a inimii.<\/p>\n

Neuronii care protejeaz\u0103 inima de stres<\/h2>\n

Cel de-al doilea grup, numit Ddah1+, i-a surprins pe cercet\u0103tori. Ini\u021bial, stimularea sau eliminarea acestor neuroni nu p\u0103rea s\u0103 produc\u0103 niciun efect.<\/p>\n

Descoperirea a venit accidental, \u00een timpul m\u0103sur\u0103rii tensiunii arteriale la un \u0219oarece lipsit de ace\u0219ti neuroni. Animalul a murit \u00een timpul procedurii.<\/p>\n

Experimente ulterioare au ar\u0103tat c\u0103 aproximativ dou\u0103 treimi dintre \u0219oarecii f\u0103r\u0103 neuroni Ddah1+ au murit atunci c\u00e2nd au fost supu\u0219i unor situa\u021bii de stres, \u00een timp ce animalele din grupul de control au supravie\u021buit. \u00cen schimb, stimularea acestor neuroni a crescut semnificativ \u0219ansele de supravie\u021buire.<\/p>\n

Posibile aplica\u021bii \u00een tratamentul bolilor de inim\u0103<\/h2>\n

Speciali\u0219tii spun c\u0103 descoperirea schimb\u0103 modul \u00een care este privit\u0103 rela\u021bia dintre creier \u0219i inim\u0103. P\u00e2n\u0103 acum se credea c\u0103 neuronii inimii doar transmit comenzile primite de la creier, \u00eens\u0103 noul studiu sugereaz\u0103 c\u0103 ace\u0219tia au func\u021bii complexe \u0219i pot proteja inima \u00een mod activ.<\/p>\n

De\u0219i cercetarea<\/a> a fost realizat\u0103 pe \u0219oareci, oamenii de \u0219tiin\u021b\u0103 au identificat aceia\u0219i markeri genetici \u0219i \u00een neuronii cardiaci umani, ceea ce sugereaz\u0103 c\u0103 mecanisme similare ar putea exista \u0219i la oameni.<\/p>\n

Autorii consider\u0103 c\u0103 \u00een\u021belegerea acestui sistem nervos al inimii ar putea duce la dezvoltarea unor terapii mai precise pentru afec\u021biuni precum infarctul miocardic, insuficien\u021ba cardiac\u0103 \u0219i tulbur\u0103rile de ritm. De asemenea, rezultatele ar putea contribui la perfec\u021bionarea procedurilor actuale de abla\u021bie cardiac\u0103 \u0219i la apari\u021bia unor noi tratamente bazate pe stimularea sistemului nervos al inimii.<\/p>\n","protected":false},"excerpt":{"rendered":"

Rezultatele studiului, publicate miercuri \u00een revista Cell, ar putea deschide calea c\u0103tre noi tratamente pentru bolile cardiovasculare. Sistemul nervos intrinsec al inimii este alc\u0103tuit dintr-o re\u021bea de neuroni localiza\u021bi \u00een … Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":704410,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts\/704409"}],"collection":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=704409"}],"version-history":[{"count":0,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts\/704409\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/media\/704410"}],"wp:attachment":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=704409"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=704409"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=704409"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}