{"id":708581,"date":"2026-08-16T17:07:04","date_gmt":"2026-08-16T17:07:04","guid":{"rendered":"https:\/\/microscopemedia.com\/?p=708581"},"modified":"2026-08-16T17:07:04","modified_gmt":"2026-08-16T17:07:04","slug":"un-mister-al-sindromului-post-covid-19-mai-aproape-de-raspuns-virusuri-latente-se-reactiveaza","status":"publish","type":"post","link":"https:\/\/microscopemedia.com\/?p=708581","title":{"rendered":"Un mister al sindromului post-COVID-19, mai aproape de r\u0103spuns: virusuri latente se reactiveaz\u0103"},"content":{"rendered":"
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O familie de virusuri pu\u021bin \u00een\u021beleas\u0103 a fost asociat\u0103 puternic cu sindromul post-COVID-19 \u0219i cu dizabilitatea fizic\u0103 persistent\u0103, oferind un posibil indiciu important cu privire la motivul pentru care unii pacien\u021bi se recupereaz\u0103 cu dificultate.<\/p>\n

Virusurile care r\u0103m\u00e2n \u00een organism ani de zile, inclusiv virusul Epstein-Barr, citomegalovirusul (CMV) \u0219i virusurile herpetice, sunt extrem de r\u0103sp\u00e2ndite, potrivit ScienceDaily<\/a>.<\/p>\n

La multe persoane, acestea nu provoac\u0103 simptome \u0219i par inofensive. \u00cens\u0103 tot mai multe dovezi sugereaz\u0103 c\u0103, atunci c\u00e2nd aceste virusuri latente se reactiveaz\u0103, ele ar putea avea un rol \u00een bolile autoimune \u0219i \u00een alte afec\u021biuni de lung\u0103 durat\u0103.<\/p>\n

Acum, cercet\u0103torii de la Boston Children\u2019s Hospital \u0219i institu\u021biile care au colaborat cu acesta au descoperit c\u0103 COVID-19 poate reactiva anumite virusuri latente la pacien\u021bii spitaliza\u021bi.<\/p>\n

Descoperirile ofer\u0103 noi informa\u021bii despre virusurile care persist\u0103 \u00een organism \u0219i ar putea contribui, \u00een cele din urm\u0103, la elaborarea unor strategii pentru prevenirea sau tratarea reactiv\u0103rii lor.<\/p>\n

Virusurile ascunse, urm\u0103rite \u00een timpul COVID-19<\/h2>\n

Studiul a urm\u0103rit 1.154 de pacien\u021bi din 20 de spitale de cercetare biomedical\u0103 din SUA \u0219i a fost conceput pentru identificarea biomarkerilor asocia\u021bi cu severitatea COVID-19 \u0219i cu evolu\u021bia pacien\u021bilor.<\/p>\n

Cercet\u0103torii au folosit secven\u021biere genomic\u0103 pentru a c\u0103uta indicii c\u0103 virusurile latente se activaser\u0103 din nou. Infec\u021biile virale care au fost eliminate de mult timp din starea activ\u0103 pot uneori s\u0103 reapar\u0103 atunci c\u00e2nd organismul este supus stresului.<\/p>\n

11 virusuri s-au reactivat dup\u0103 internarea \u00een spital<\/h2>\n

\u00cen primele 40 de zile de la internarea pacien\u021bilor \u00een spital, cercet\u0103torii au identificat 11 virusuri care s-au reactivat. Printre cele detectate cel mai frecvent s-au num\u0103rat virusul Epstein-Barr, virusul herpes simplex 1, citomegalovirusul \u0219i virusurile din familia Anelloviridae.<\/p>\n

O descoperire s-a remarcat \u00een mod deosebit. Reactivarea virusurilor din familia Anelloviridae, o familie de virusuri pu\u021bin \u00een\u021beleas\u0103 care r\u0103m\u00e2ne de obicei latent\u0103 la aproximativ 90% din popula\u021bie, a prezentat o asociere semnificativ\u0103 cu dizabilitatea fizic\u0103 pe termen lung \u0219i cu sindromul post-COVID-19.<\/p>\n

Inflama\u021bia ar putea declan\u0219a reactivarea virusurilor<\/h2>\n

Analiza probelor de s\u00e2nge a scos la iveal\u0103 \u0219i un tipar nea\u0219teptat \u00een cazul virusului Epstein-Barr \u0219i al citomegalovirusului. \u00cen loc s\u0103 par\u0103 c\u0103 se reactiveaz\u0103 ca urmare a suprim\u0103rii sistemului imunitar, aceste virusuri au p\u0103rut s\u0103 devin\u0103 active ca r\u0103spuns la inflama\u021bie.<\/p>\n

Cercet\u0103torii spun c\u0103 aceast\u0103 descoperire indic\u0103 un mecanism surprinz\u0103tor \u0219i pune sub semnul \u00eentreb\u0103rii ideea potrivit c\u0103reia reactivarea viral\u0103 cronic\u0103 apare \u00een principal din cauza imunosupresiei. Rezultatele arat\u0103 c\u0103 virusurile latente se pot reactiva frecvent la persoane al c\u0103ror sistem imunitar pare s\u0103 func\u021bioneze normal \u00een timpul unei boli severe, \u00een special atunci c\u00e2nd inflama\u021bia sistemic\u0103 este crescut\u0103.<\/p>\n

Cercet\u0103torii inten\u021bioneaz\u0103 s\u0103 investigheze \u00een continuare modul \u00een care sistemul imunitar reac\u021bioneaz\u0103 la aceste virusuri reactivate pe parcursul infec\u021biei cu COVID-19<\/a>. Obiectivul lor este s\u0103 identifice tratamente eficiente \u0219i s\u0103 stabileasc\u0103 momentul optim pentru eventualele interven\u021bii.<\/p>\n","protected":false},"excerpt":{"rendered":"

O familie de virusuri pu\u021bin \u00een\u021beleas\u0103 a fost asociat\u0103 puternic cu sindromul post-COVID-19 \u0219i cu dizabilitatea fizic\u0103 persistent\u0103, oferind un posibil indiciu important cu privire la motivul pentru care unii … Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":708582,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"Default","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts\/708581"}],"collection":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=708581"}],"version-history":[{"count":0,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/posts\/708581\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=\/wp\/v2\/media\/708582"}],"wp:attachment":[{"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=708581"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=708581"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/microscopemedia.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=708581"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}